Whether you’ve recently been diagnosed
with psoriasis or you’ve been living with it for years,

you’re looking for answers, and we’re here to help. While our site is designed to be a valuable resource along your journey, establishing an ongoing partnership with your healthcare provider will always be the best way to manage your specific and ever-changing condition.


What is psoriasis?

Psoriasis is a chronic skin condition that causes raised, red or silvery, scaly patches (plaques) to appear on the skin. It is an auto-immune disease in which patients shed their skin too quickly, causing dead skin cells to pile up on the surface. Normal skin cell turnover usually takes about a month, but for psoriasis patients the turnover can happen in only a few days.


Who gets it? Why?

Affecting over 7 million adults in the United States, psoriasis is a common skin condition that develops in both men and women at equal rates – often first appearing between the ages of 15 and 35. While scientists differ on its exact cause, genetics and the immune system both play major roles in the development of plaque psoriasis.

What are the types of psoriasis?

Although plaque psoriasis is the most common form of the disease, there are many other types that you should be aware of. Talk to your doctor if you recognize any of the symptoms described below.

  • 1

    Plaque psoriasis

    Plaque psoriasis is the most common and can appear as red bumpy patches that are covered with a silver-white buildup of dead skin cells
    • usually appears on scalp, knees, and lower back
    • can be itchy and painful and may crack and bleed
    DUOBRII Lotion is approved to treat plaque psoriasis
  • 2

    Scalp psoriasis

    The name is somewhat misleading since scalp psoriasis can also appear on the forehead, neck and around the ears. The skin of the scalp is thicker so a different medication is used to treat it.

    DUOBRII Lotion is approved to treat plaque psoriasis

  • 3

    Nail psoriasis

    Nail psoriasis can cause a number of problems like pitting, discoloration and even the separation of the nail from the cuticle. Since nail injury may trigger or worsen psoriasis, it is important to keep your nails protected.

    DUOBRII Lotion is approved to treat plaque psoriasis

  • 4

    Guttate [GUH-tate] psoriasis

    Guttate psoriasis is a form of psoriasis that often starts in childhood or young adulthood, and can be triggered by a strep infection. This is the second most common type of psoriasis, after plaque psoriasis.

    DUOBRII Lotion is approved to treat plaque psoriasis

  • 5

    Inverse psoriasis

    Inverse psoriasis can happen in people with other types of psoriasis already on their body. It appears as bright red lesions on skin folds such as behind the knee, under the arms, or in the groin area.

    DUOBRII Lotion is approved to treat plaque psoriasis

  • 6

    Pustular [PUHS-choo-lar] psoriasis

    Pustular psoriasis appears anywhere on the body, but usually on the hands or feet, as white blisters (“pustules”) surrounded by red skin. These blisters are not infected and you can’t spread it to anyone since it is not contagious.

    DUOBRII Lotion is approved to treat plaque psoriasis

  • 7

    Erythrodermic [eh-REETH-ro-der-mik] psoriasis

    Erythrodermic psoriasis is a very severe but rare type of psoriasis. This type tends to occur as redness all over the body and is very itchy and painful. It can sometimes even cause the skin to come off in sheets.

    DUOBRII Lotion is approved to treat plaque psoriasis


Psoriasis “triggers” are external factors that initiate the overproduction of skin cells in patients, but they are not universal for all. A trigger for one patient may not affect another.

  • Stress
  • Injury to skin
  • Certain medications
  • Bacterial infection
  • Smoking tobacco
  • Allergies
  • Cold, dry weather or excess sunlight
  • Certain foods like whole milk, gluten, citrus fruits, and fatty foods
  • Drinking alcohol
*List of triggers is not comprehensive and not all triggers are scientifically proven.

How is it diagnosed?

Your healthcare provider will assess the severity of your psoriasis. Depending on the percentage of your body surface area (BSA) that is affected by recurring scaly patches, psoriasis is categorized as mild, moderate, or severe. These may be managed through proper treatment and medical supervision.


What are the available
treatment options?

Every patient’s journey is different, so finding the right psoriasis treatment for you may not happen immediately. Fortunately,
healthcare providers are becoming more aware of the impact psoriasis can have on a patient’s daily life,
and pharmaceutical companies and researchers are continually investigating and developing
new solutions to answer these challenges.

Your healthcare provider will play a vital role in the management of your condition and may
suggest one of the treatment options below to control your psoriasis.

  • Topicals

    Applied to the skin and usually the first treatment after initial diagnosis.
  • Orals

    Systemic treatment option that can be swallowed.
  • Biologics

    Typically prescribed for moderate-to-severe psoriasis when other treatments have failed.
  • Phototherapy

    Often referred to as “light therapy,” the skin is exposed to ultraviolet light on a regular basis and under medical supervision. Typically performed in a doctor’s office or clinic, this treatment can also be done at home with a phototherapy unit.

What are other health issues related to psoriasis?

If you have psoriasis, you may have a greater chance of having other health conditions as well.
If you think you have symptoms of one
of these conditions, talk to your doctor.

  • Psoriatic (sore-EE-at-ic) arthritis, which can cause pain and swelling in your joints
  • Cardiovascular disease
  • Obesity
  • Diabetes
  • Depression
  • High blood pressure
  • Inflammatory bowel disorders, such as Crohn’s disease
  • Certain cancers, such as lymphoma and nonmelanoma skin cancer
  • Certain conditions such as osteoporosis (weak bones), kidney disease, liver disease, or inflammatory eye disease

Living with psoriasis:
Tips that
can help you cope

In addition to treatment, there are some things you can do on a daily basis
that can help you stay healthy and manage your psoriasis.


Moisturize! Ask your dermatologist about the types of lotions and bath soaps that can soothe your skin.

Eat healthy and exercise. This is important since people with psoriasis are at higher risk for diabetes and other conditions. There are many factors to consider when choosing what to eat. So ask your doctor what a healthy diet means for you.

Drink less alcohol, smoke less, and watch your weight. Drinking, smoking, and gaining weight may worsen the symptoms of psoriasis.

Watch out for joint stiffness. Pay attention to whether your joints feel sore or stiff, especially in the morning. These can be signs of psoriatic arthritis.

Pay attention to your nails. Take a look at your nails often to see if the nail beds are yellowish-orange in color or have pits or ridges. These can also be signs of psoriatic arthritis.

Talk to someone. It is normal for people with psoriasis to experience feelings of sadness, lack of sleep, and trouble focusing on work or even basic tasks. You may also feel self-conscious about the scaly patches on your skin. If so, it’s important to talk to someone and not suffer in silence. You should never feel afraid to ask for help or talk to someone.

Talk to your doctor about your treatment. If you have questions about your medicine including side effects or the cost of treatment, talk to your doctor. It’s important to call your doctor before stopping treatment.

Discuss your options with your healthcare professional

All psoriasis treatments can have side effects, so be sure to talk about them with your provider to see which one is right for you.

View or download the Doctor Discussion Guide

What is DUOBRII® Lotion?

Important Safety Information

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DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat people with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy.

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.
What should I avoid during treatment with DUOBRII?
  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.
DUOBRII may cause side effects, including:
  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Please click here for full Prescribing Information, including Patient Information.