Understanding your plaque psoriasis. Patient covers the plaque psoriasis on her arm
Understanding your plaque psoriasis. Patient covers the plaque psoriasis on her arm Understanding your plaque psoriasis. Patient covers the plaque psoriasis on her arm Understanding your plaque psoriasis. Patient covers the plaque psoriasis on her arm

You're living with psoriasis,
and you're looking for answers

We’re here to help. Establishing an ongoing partnership with your doctor will always be the best way to manage your psoriasis and overall health.

What is Psoriasis?

Understanding how psoriasis affects the skin

Psoriasis is a chronic skin condition that causes raised, red or silvery, scaly patches (plaques) to appear on the skin. It is an auto-immune disease in which patients shed their skin too quickly, causing dead skin cells to pile up on the surface. Normal skin cell turnover usually takes about a month, but for patients with psoriasis the turnover can happen in only a few days.

Illustration of skin with plaque psoriasis vs healthy skin
Illustration of 8 million psoriasis cases in the US

Who gets it and why?

Affecting over 8 million adults in the United States, psoriasis is a common skin condition that develops in both men and women at equal rates – often first appearing between the ages of 15 and 35. While scientists differ on its exact cause, genetics and the immune system both play major roles in the development of psoriasis.

What are the types of psoriasis?

Plaque psoriasis is the most common form of the disease; however, there are many other types that you should be aware of. DUOBRII Lotion is only approved to treat adults with plaque psoriasis. Talk to your doctor if you recognize any of the symptoms described below.

  • 1

    Plaque psoriasis

    Plaque psoriasis is the most common and can appear as red bumpy patches that are covered with a silver-white buildup of dead skin cells. Plaque psoriasis:
    • Usually appears on scalp, knees, and lower back
    • Can be itchy and painful and may crack and bleed
  • 2

    Scalp psoriasis

    The name is somewhat misleading since scalp psoriasis can also appear on the forehead, neck and around the ears. The skin of the scalp is thicker so a specific medication is used to treat it.
  • 3

    Nail psoriasis

    Nail psoriasis can cause a number of problems like pitting, discoloration and even the separation of the nail from the cuticle. Since nail injury may trigger or worsen psoriasis, it is important to keep your nails protected.
  • 4

    Guttate psoriasis

    Guttate [GUH-tate] psoriasis is a form of psoriasis that often starts in childhood or young adulthood, and can be triggered by a strep infection. This is the second most common type of psoriasis, after plaque psoriasis.
  • 5

    Inverse psoriasis

    Inverse psoriasis can happen in people with other types of psoriasis already on their body. It appears as bright red lesions on skin folds such as behind the knees, under the arms, or in the groin area.
  • 6

    Pustular psoriasis

    Pustular [PUHS-choo-lar] psoriasis appears anywhere on the body, but usually on the hands or feet, as white blisters (“pustules”) surrounded by red skin. These blisters are not infected or contagious.
  • 7

    Erythrodermic psoriasis

    Erythrodermic [eh-REETH-ro-der-mik] psoriasis is a very severe but rare type of psoriasis. This type tends to occur as redness all over the body and is very itchy and painful. It can sometimes even cause the skin to come off in sheets.

Visit Psoriasis.org

For more information on the different types of psoriasis.

Triggers

Halobetasol and tazarotene characters identify plaque psoriasis triggers

What are common causes of psoriasis flares?

Psoriasis triggers are external factors that initiate the overproduction of skin cells in patients, but they are not universal for all. A trigger for one patient may not affect another.

  • Stress
  • Injury to skin
  • Certain medications
  • Bacterial infection
  • Smoking tobacco
  • Allergies
  • Cold, dry weather or excess sunlight
  • Certain foods like whole milk, gluten, citrus fruits, and fatty foods
  • Drinking alcohol
List of triggers is not comprehensive and not all triggers are scientifically proven.

How is it Diagnosed?

Evaluating the severity of psoriasis

Your doctor will assess the severity of your psoriasis. Depending on the percentage of your body surface area (BSA) that is affected by recurring scaly patches, psoriasis is categorized as mild, moderate, or severe. All of these can often be managed through proper treatment and medical supervision. To get an idea of how to measure BSA, your entire hand is equal to about 1% of your BSA.

Mild plaque psoriasis covers < 3% of the body
Moderate plaque psoriasis covers 3% - 10% of the body
Severe plaque psoriasis covers > 10% of the body

In addition to BSA, the severity of your plaque psoriasis is measured by how it affects your quality of life. Any amount can have an impact on day-to-day activities and feelings, so make sure to be completely honest with your doctor when getting assessed.

Treatment Options

What are the available treatment options?

Every patient’s journey is different, so finding the right psoriasis treatment for you may not happen immediately. Keep in mind that new solutions are continually being developed.

Your doctor may suggest one of the following treatment options to help get your psoriasis under control.

  • Topical treatments

    Topicals

    Applied to the skin and usually the first treatment after initial diagnosis. Topical treatments can often be used in conjunction with other types of therapies. DUOBRII Lotion is a topical treatment.
  • Oral treatments

    Orals

    Systemic treatment option that is taken by mouth.
  • Biologic treatments

    Biologics

    Treatment given by injection or intravenous infusion. Typically prescribed for moderate-to-severe psoriasis when other treatments have failed.
  • Phototherapy/light treatment

    Phototherapy

    Often referred to as “light therapy,” the skin is exposed to ultraviolet light on a regular basis and usually under medical supervision.

What are other health issues related to psoriasis?

If you have psoriasis, you may have a greater chance of having other health conditions as well. If you think you have symptoms of one of these conditions, talk to your doctor.

  • Psoriatic (sore-EE-at-ic) arthritis, which can cause pain and swelling in your joints
  • Cardiovascular disease
  • Obesity
  • Diabetes
  • Depression
  • High blood pressure
  • Inflammatory bowel disorders, such as Crohn’s disease
  • Certain cancers, such as lymphoma and nonmelanoma skin cancer
  • Certain conditions such as osteoporosis (weak bones), kidney disease, liver disease, or inflammatory eye disease

Finding a doctor
near you

Use this tool to find a dermatologist in your area.

Discussing your psoriasis
with your doctor

Whether you have been prescribed DUOBRII Lotion or not, this Doctor Discussion Guide will help you have a productive conversation with your doctor.

Up next…

Learn how you may be able to save on DUOBRII Lotion.

See More

What is DUOBRII® Lotion?

Important Safety Information

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy.

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.
What should I avoid during treatment with DUOBRII?
  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.
DUOBRII may cause side effects, including:
  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Please click here for full Prescribing Information, including Patient Information.

*This offer does not apply to any state or federal government insurance program. Additional restrictions may apply. For more details go to OrthoRxAccess.com.