Savings Offer

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Exclusively at Walgreens and other participating independent pharmacies

Most eligible commercially insured
patients pay as little as a:

$0 Co-Pay*

Ortho Dermatologics Rx Access Program offers DUOBRII Lotion savings

For eligible patients whose commercial insurance does not cover DUOBRII Lotion†, patients will pay as little as a $25 co-pay. This offer is available on up to 6 refills of your prescription.

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OrthoRxAccess.com

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Ortho Dermatologics Rx Access Program offers DUOBRII Lotion savings

*This offer is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan, or any other federal or state healthcare programs. This offer is good only in the U.S. at retail pharmacies owned and operated by Walgreen Co. (or its affiliates) or other participating independent retail pharmacies. This offer is not valid where otherwise prohibited, taxed or otherwise restricted. Click here for full Eligibility Terms and Conditions.

†Insured not covered is defined as a patient who has commercial insurance but the drug is not covered on the plan’s formulary or has an NDC block, prior authorization, step edit or other restriction that has not been met.

Downloadable Resources

How to use DUOBRII Lotion

Detailed instructions and tips are available in this helpful guide to using DUOBRII Lotion.

Download
Guide to using DUOBRII Lotion

Discussing your psoriasis
with your doctor

Ensure you get the best treatment by knowing the right questions to ask your doctor. Use this Doctor Discussion Guide to get started.

Download
Doctor discussion guide for plaque psoriasis

Frequently Asked Questions

Q. What is DUOBRII Lotion?

A: DUOBRII Lotion is a prescription medicine made up of a combination of halobetasol propionate and tazarotene that is used on the skin to treat plaque psoriasis in adults. Do not use DUOBRII Lotion in your mouth, eyes or vagina.

Q. Can I use DUOBRII Lotion if I’m pregnant or breastfeeding?

A: You must not be pregnant when you start using DUOBRII Lotion or become pregnant during treatment with DUOBRII Lotion. DUOBRII Lotion may cause birth defects if used during pregnancy.

For females who are able to get pregnant:

  • Your doctor should order a pregnancy test for you within 2 weeks before you begin treatment with DUOBRII Lotion to be sure that you are not pregnant.
  • Begin treatment with DUOBRII Lotion during a normal menstrual period.
  • Use an effective form of birth control during treatment with DUOBRII Lotion. Talk with your doctor about birth control options to prevent pregnancy during treatment with DUOBRII Lotion.
  • Stop using DUOBRII Lotion and tell your doctor right away if you become pregnant while using DUOBRII Lotion.
Q. How long can I use DUOBRII Lotion?

A: Unlike using potent-to-superpotent steroids alone, you can use DUOBRII Lotion once daily, only until your psoriasis is under control. Stop using when your skin becomes clear or if you experience side effects.

Once clear, you may stay that way for up to 3 months after using DUOBRII Lotion.

Q. Who else should not use DUOBRII Lotion?

A: Do not use DUOBRII Lotion on skin where you have eczema because it may cause severe irritation.

If you have a sunburn, do not use DUOBRII Lotion until fully recovered.

If you have considerable sun exposure due to your occupation or are sensitive to sunlight, exercise particular caution when using DUOBRII Lotion.

Q. What other safety information do I need to know?

A: DUOBRII Lotion may cause HPA axis suppression, which is when your body is unable to make enough cortisol, a hormone that is important to several body systems. Your doctor will monitor you for symptoms during treatment with DUOBRII Lotion.

Q. What should I tell my doctor before using DUOBRII Lotion?

A: Before you use DUOBRII Lotion, tell your doctor if you:

  • have eczema or any other skin problems.
  • have a skin infection. You may need medicine to treat the skin infection before using DUOBRII.
  • have diabetes.
  • have adrenal gland problems.
  • have liver problems.
  • are breastfeeding or plan to breastfeed. It is not known if DUOBRII passes into your breast milk. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple or areola to avoid getting DUOBRII into your baby’s mouth.

DUOBRII Lotion cannot be used during pregnancy (see question above about use during pregnancy).

Q. Can I use DUOBRII Lotion if I’m taking other medications for psoriasis?

A: Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal supplements, and cosmetics. Especially tell your doctor if you take corticosteroids by mouth, or injection, or use other products on your skin that contain corticosteroids. Certain medicines may make your skin more sensitive to sunlight. Ask your doctor for a list of these medicines if you are not sure.

Q. What should I avoid while using DUOBRII Lotion?

A: Avoid sunlight, including sunlamps and tanning beds, during your treatment with DUOBRII Lotion. DUOBRII Lotion can make your skin more sensitive to the sun and the light from sunlamps and tanning beds. You could get severe sunburn. Use sunscreen, and wear a hat and clothes that cover your skin if you have to be in sunlight.

  • Talk to your doctor if you get sunburn during treatment with DUOBRII. If you do get sunburn, do not use DUOBRII until your sunburn is healed.

Avoid using DUOBRII on skin with eczema because it may cause severe irritation.

Q. What are the possible side effects of DUOBRII Lotion?

A: DUOBRII may cause side effects, including:

  • See “What is the most important information I should know about DUOBRII Lotion?”
  • DUOBRII Lotion can pass through your skin. Too much DUOBRII Lotion passing through your skin can cause adrenal glands to stop working.
  • Cushing’s syndrome, a condition that happens when your body is exposed to too much of the hormone cortisol.
  • High blood sugar (hyperglycemia).
  • Effects of growth and weight in children.
  • Skin irritation. DUOBRII may cause increased skin irritation. Tell your doctor if you develop any skin irritation during your treatment with DUOBRII. If you develop skin irritation, your doctor may tell you to interrupt or stop using DUOBRII, or tell you to use DUOBRII less often.
  • Sensitivity to light and risk of sunburn. See “What should I avoid during treatment with DUOBRII Lotion?”
  • Vision problems. DUOBRII may increase your chance of developing cataract(s) and glaucoma. Tell your doctor if you have blurred vision or other vision problems during your treatment with DUOBRII.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

These are not all of the possible side effects of DUOBRII.

Q. What are the active ingredients in DUOBRII Lotion?

A: DUOBRII Lotion is a combination product containing halobetasol propionate and tazarotene as the active ingredients in a white to off-white lotion formulation.

Q. What other ingredients are in DUOBRII Lotion?

A: Other ingredients in DUOBRII Lotion are carbomer copolymer type B, carbomer homopolymer type A, diethyl sebacate, edetate disodium dihydrate, light mineral oil, methylparaben, propylparaben, purified water, sodium hydroxide, sorbitan monooleate and sorbitol solution, 70%.

Q. Can I just use an over-the-counter lotion?

A: There are many medications available to treat psoriasis. Talk to your doctor about which medications are right for you.

Q. Where on my body can I not use DUOBRII Lotion?

A: DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina. DUOBRII Lotion also should not be used on the face, groin, or in the armpit. Do not apply it to skin that has eczema.

Q. Can I use a moisturizer while using DUOBRII Lotion?

A: You may use a cream or lotion to soften or moisten your skin as often as desired, except within an hour of applying DUOBRII Lotion. However, make sure to tell your doctor about any cosmetics you use, including moisturizers, creams, lotions, or products that can dry out your skin.

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What is DUOBRII® Lotion?

Important Safety Information

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.

What is DUOBRII® Lotion?

DUOBRII (halobetasol propionate and tazarotene) Lotion, 0.01%/0.045%, is a prescription medicine used on the skin (topical) to treat adults with plaque psoriasis. It is not known if DUOBRII Lotion is safe and effective in children.

Important Safety Information

  • DUOBRII Lotion is for use on the skin only; do not use it in your mouth, eyes, or vagina.
What is the most important Information I should know about DUOBRII Lotion?

DUOBRII Lotion may cause birth defects if used during pregnancy.

A negative pregnancy test must be obtained before females of child-bearing age start using DUOBRII Lotion and they must use effective birth control during treatment. Begin treatment during a normal menstrual period.

Stop using DUOBRII Lotion and tell your healthcare provider right away if you become pregnant while using DUOBRII Lotion.

Before you use DUOBRII Lotion, tell your healthcare provider if you:

  • have eczema or any other skin problems, including skin infections, which may need to be treated before using DUOBRII.
  • have diabetes, adrenal gland problems or liver problems.
  • are breastfeeding or plan to breastfeed. If you use DUOBRII and breastfeed, do not apply DUOBRII to your nipple area.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

  • Especially tell your healthcare provider if you take corticosteroids by mouth or injection or use other skin products that contain corticosteroids.
  • Ask your healthcare provider for a list of medicines that may make your skin more sensitive to sunlight.
What should I avoid during treatment with DUOBRII?
  • To avoid a severe sunburn, avoid sunlight, including sunlamps and tanning beds, as much as possible, and use sunscreen, protective clothing and a hat while in sunlight. Talk to your healthcare provider if you get sunburn, and do not use DUOBRII Lotion until your sunburn is healed.
  • Avoid using DUOBRII on skin with eczema because it may cause severe irritation.
DUOBRII may cause side effects, including:
  • If too much DUOBRII passes through your skin it can cause adrenal glands to stop working
  • Cushing’s syndrome, a condition from too much exposure to the hormone cortisol
  • High blood sugar (hyperglycemia)
  • Effects of growth and weight in children
  • Skin irritation. If you get too much skin irritation at the site of application, your healthcare provider may tell you to interrupt or stop using DUOBRII or to use it less often.
  • Vision problems, including an increased chance of developing cataracts and glaucoma. Tell your healthcare provider about any vision problems during treatment.

The most common side effects of DUOBRII Lotion include: redness, itching, swelling, burning, stinging, application site pain, inflamed hair follicles (folliculitis), thinning of the skin (atrophy), peeling and rash.

To report SUSPECTED ADVERSE REACTIONS, contact Ortho Dermatologics at 1-800-321-4576 or FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

Please click here for full Prescribing Information, including Patient Information.

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